On a rare occasion you could be facing the following error message when opening the Qsys Configurator.
When this happen, Uninstall your Qsys Designer software and Re-install it.
You can find the various versions of Qsys Designer at the following link: https://www.qsc.com/de/systems/produkte/q-systm-plattform/software/q-systm-designer-software/archiv/